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Complementing this finding, Siracusa et al

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Neurons, like most other cells, do not possess transport mechanisms for GSH and elevation of extracellular GSH may pose potential toxicity problems that increase neuronal vulnerability during ischemia, while the encapsulation of GSH into lipid vesicles may avoid the potential toxicity to neurons associated with extracellular GSH elevation and may facilitate drug delivery to cells as has been shown for other liposomal preparations [137, 138]